Thiamine-triphosphatase is an enzyme involved in thiamine metabolism. It catalyzes the chemical reaction
thiamine triphosphate + H2O ⇌ {\displaystyle \rightleftharpoons } thiamine diphosphate + phosphate This enzyme belongs to the family of acid anhydride hydrolases, specifically those acting on phosphorus-containing anhydrides. Its systematic name is thiamine triphosphate phosphohydrolase.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 2JMU.
See also Thiamine-diphosphate kinase
References
Hashitani Y, Cooper JR (1972). "The partial purification of thiamine triphosphatase from rat brain". J. Biol. Chem. 247 (7): 2117–9. doi:10.1016/S0021-9258(19)45498-7. PMID 4335862.
