In enzymology, a thiol oxidase (EC 1.8.3.2) is an enzyme that catalyzes the chemical reaction
4 R'C(R)SH + O2 ⇌ {\displaystyle \rightleftharpoons } 2 R'C(R)S-S(R)CR' + 2 H2O Thus, the two substrates of this enzyme are R'C(R)SH and O2, whereas its two products are R'C(R)S-S(R)CR' and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is thiol:oxygen oxidoreductase. This enzyme is also called sulfhydryl oxidase.
References
AURBACH GD, JAKOBY WB (1962). "The multiple functions of thiooxidase". J. Biol. Chem. 237 (2): 565–8. doi:10.1016/S0021-9258(18)93962-1. PMID 13863296. NEUFELD HA, GREEN LF, LATTERELL FM, WEINTRAUB RL (1958). "Thioxidase, a new sulfhydryl-oxidizing enzyme from Piricularia oryzae and Polyporus versicolor". J. Biol. Chem. 232 (2): 1093–9. doi:10.1016/S0021-9258(19)77424-9. PMID 13549489.
