Thymol blue (thymolsulfonephthalein) is a brownish-green or reddish-brown crystalline powder that is used as a pH indicator. It is insoluble in water but soluble in alcohol and dilute alkali solutions.
It transitions from red to yellow at pH 1.2–2.8 and from yellow to blue at pH 8.0–9.6. It is usually a component of universal indicator. At wavelength (378 - 382) nm, extinction coefficient > 8000 and at wavelength (298 - 302) nm, the extinction coefficient > 12000.
Structures Thymol blue undergoes chemical changes in response to varying pH:
As a result, its visible color also changes:
Safety It may cause irritation. Its toxicological properties have not been fully investigated. Harmful if swallowed, Acute Toxicity. Only Hazardous when percent values are above 10%.
Bibliography Merck. "Thymol Blue." The Merck Index. 14th ed. 2006. Accessed via web on 2007-02-25.
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