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Timeline of medicine and medical technology

This is a timeline of the history of medicine and medical technology.

Antiquity c. 12000 BC – The earliest known example of dental caries manipulation is found in a Paleolithic man in Northern Italy. 7300 - 6200 BC – First evidence of trepanation, with signs of healing suggesting survival, identified in a skull in Ukraine. 3350 - 3105 BC - Ötzi dies with a parasitic whipworm infection while carrying Piptoporus betulinus, a type of birch fungus that contains toxic resins against whipworm and induces diarrhea. It has been likely used an anthelmintic medication. 3000 BC – The origins of Ayurveda traced back to around 3,000 BCE. c. 2600 BC – Imhotep the priest-physician to be later deified as the Egyptian god of medicine. 2500 BC – Egyptian inscription speaks of Iry as eye-doctor of the palace, palace physician of the belly, guardian of the royal bowels, and he who prepares the important medicine (name cannot be translated) and knows the inner juices of the body. 1900–1600 BC Akkadian clay tablets on medicine survive primarily as copies from Ashurbanipal's library at Nineveh. 1800 BC – Code of Hammurabi sets out fees for surgeons and punishments for malpractice 1800 BC – Kahun Gynecological Papyrus 1600 BC – Hearst papyrus, coprotherapy and magic 1551 BC – Ebers Papyrus, coprotherapy and magic 1500 BC – Saffron used as a medicine on the Aegean island of Thera in ancient Greece 1500 BC – Edwin Smith Papyrus, an Egyptian medical text and the oldest known surgical treatise (no true surgery) no magic 1300 BC – Brugsch Papyrus and London Medical Papyrus 1250 BC – Asklepios 9th century – Hesiod reports an ontological conception of disease via the Pandora myth. Disease has a "life" of its own but is of divine origin. 8th century – Homer tells that Polydamna supplied the Greek forces besieging Troy with healing drugs. Homer also tells about battlefield surgery Idomeneus tells Nestor after Machaon has fallen: A surgeon who can cut out an arrow and heal the wound with his ointments is worth a regiment. 700 BC – Cnidos medical school; also one at Cos 500 BC – Darius I orders the restoration of the House of Life (First record of a (much older) medical school) 500 BC – Bian Que becomes the earliest physician known to use acupuncture and pulse diagnosis 500 BC – The Sushruta Samhita is published, laying the framework for Ayurvedic medicine, giving many surgical procedures for first time such as lithotomy, forehead flap rhinoplasty, otoplasty and many more. c. 490 – c. 430 – Empedocles four elements 500 BC – Pills are used. They have been presumably invented so that measured amounts of a medicinal substance could be delivered to a patient. 510–430 BC – Alcmaeon of Croton scientific anatomic dissections. He studies the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence. He distinguishes veins from the arteries and has at least vague understanding of the circulation of the blood. Variously described by modern scholars as Father of Anatomy; Father of Physiology; Father of Embryology; Father of Psychology; Creator of Psychiatry; Founder of Gynecology; and as the Father of Medicine itself. There is little evidence to support the claims but he is, nonetheless, important. fl. 425 BC – Diogenes of Apollonia c. 484 – 425 BC – Herodotus tells us Egyptian doctors were specialists: Medicine is practiced among them on a plan of separation; each physician treats a single disorder, and no more. Thus the country swarms with medical practitioners, some undertaking to cure diseases of the eye, others of the head, others again of the teeth, others of the intestines, and some those which are not local. 496 – 405 BC – Sophocles "It is not a learned physician who sings incantations over pains which should be cured by cutting." 420 BC – Hippocrates of Cos maintains that diseases have natural causes and puts forth the Hippocratic Oath. Origin of rational medicine.

Medicine after Hippocrates c. 400 BC – 1 BC – The Huangdi Neijing (Yellow Emperor's Classic of Internal Medicine) is published, laying the framework for traditional Chinese medicine 4th century BC – Philistion of Locri Praxagoras distinguishes veins and arteries and determines only arteries pulse 375–295 BC – Diocles of Carystus 354 BC – Critobulus of Cos extracts an arrow from the eye of Phillip II, treating the loss of the eyeball without causing facial disfigurement. 3rd century BC – Philinus of Cos founder of the Empiricist school. Herophilos and Erasistratus practice androtomy. (Dissecting live and dead human beings) 280 BC – Herophilus Dissection studies the nervous system and distinguishes between sensory nerves and motor nerves and the brain. also the anatomy of the eye and medical terminology such as (in Latin translation "net like" becomes retiform/retina. 270 – Huangfu Mi writes the Zhēnjiǔ jiǎyǐ jīng (The ABC Compendium of Acupuncture), the first textbook focusing solely on acupuncture 250 BC – Erasistratus studies the brain and distinguishes between the cerebrum and cerebellum physiology of the brain, heart and eyes, and in the vascular, nervous, respiratory and reproductive systems 219 – Zhang Zhongjing publishes Shang Han Lun (On Cold Disease Damage) 200 BC – the Charaka Samhita uses a rational approach to the causes and cure of disease and uses objective methods of clinical examination 124 – 44 BC – Asclepiades of Bithynia 116 – 27 BC – Marcus Terentius Varro Prototypal germ theory of disease. 1st century AD – Rufus of Ephesus; Marcellinus a physician of the first century AD; Numisianus 23 – 79 AD – Pliny the Elder writes Natural History c. 25 BC – c. 50 AD – Aulus Cornelius Celsus Medical encyclopedia 50 – 70 AD – Pedanius Dioscorides writes De Materia Medica – a precursor of modern pharmacopoeias that was in use for almost 1600 years 2nd century AD Aretaeus of Cappadocia 98 – 138 AD – Soranus of Ephesus 129 – 216 AD – Galen – Clinical medicine based on observation and experience. The resulting tightly integrated and comprehensive system, offering a complete medical philosophy dominated medicine throughout the Middle Ages and until the beginning of the modern era.

After Galen 200 AD

fl. before AD 210 – Fabulla or Fabylla, medical writer d. 260 – Gargilius Martialis, short Latin handbook on Medicines from Vegetables and Fruits 4th century Magnus of Nisibis, Alexandrian doctor and professor book on urine 325 – 400 – Oribasius 70 volume encyclopedia 362 – Julian orders xenones built, imitating Christian charity (proto hospitals) 369 – Basil of Caesarea founded at Caesarea in Cappadocia an institution (hospital) called Basileias, with several buildings for patients, nurses, physicians, workshops, and schools 375 – Ephrem the Syrian open a hospital at Edessa They spread out and specialized nosocomia for the sick, brephotrophia for foundlings, orphanotrophia for orphans, ptochia for the poor, xenodochia for poor or infirm pilgrims, and gerontochia for the old. 400 – The first hospital in Latin Christendom is founded by Fabiola at Rome 420 – Caelius Aurelianus a doctor from Sicca Veneria (El-Kef, Tunisia) handbook On Acute and Chronic Diseases in Latin. 447 – Cassius Felix of Cirta (Constantine, Ksantina, Algeria), medical handbook drew on Greek sources, Methodist and Galenist in Latin 480 – 547 Benedict of Nursia founder of "monastic medicine" 484 – 590 – Flavius Magnus Aurelius Cassiodorus fl. 511 – 534 – Anthimus Greek: Ἄνθιμος 536 – Sergius of Reshaina (died 536) – A Christian theologian-physician who translated thirty-two of Galen's works into Syriac and wrote medical treatises of his own 525 – 605 – Alexander of Tralles Alexander Trallianus 500 – 550 – Aetius of Amida Encyclopedia 4 books each divided into 4 sections second half of 6th century building of xenodocheions/bimārestāns by the Nestorians under the Sasanians, would evolve into the complex secular "Islamic hospital", which combined lay practice and Galenic teaching 550 – 630 Stephanus of Athens 560 – 636 – Isidore of Seville c. 620 Aaron of Alexandria Syriac writes 30 books on medicine, the "Pandects". He is the first author in antiquity who mentions the diseases of smallpox and measles translated by Māsarjawaih a Syrian Jew and Physician, into Arabic about A. D. 683 c. 630 – Paul of Aegina Encyclopedia in 7 books very detailed surgery used by Albucasis 790 – 869 – Leo Itrosophist also Mathematician or Philosopher wrote "Epitome of Medicine" c. 800 – 873 – Al-Kindi (Alkindus) De Gradibus 820 – Benedictine hospital founded, School of Salerno would grow around it d. 857 – Mesue the elder (Yūḥannā ibn Māsawayh) Syriac Christian c. 830 – 870 – Hunayn ibn Ishaq (Johannitius) Syriac-speaking Christian also knows Greek and Arabic. Translator and author of several medical tracts. c. 838 – 870 – Ali ibn Sahl Rabban al-Tabari, writes an encyclopedia of medicine in Arabic. c. 910d – Ishaq ibn Hunayn 9th century – Yahya ibn Sarafyun a Syriac physician Johannes Serapion, Serapion the Elder c. 865 – 925 – Rhazes pediatrics, and makes the first clear distinction between smallpox and measles in his al-Hawi. d. 955 – Isaac Judaeus Isḥāq ibn Sulaymān al-Isrāʾīlī Egyptian born Jewish physician 913 – 982 – Shabbethai Donnolo alleged founding father of School of Salerno writes in Hebrew d. 982 – 994 – 'Ali ibn al-'Abbas al-Majusi Haly Abbas 1000 – Albucasis (936–1018) surgery Kitab al-Tasrif, surgical instruments. d. 1075 – Ibn Butlan Christian physician of Baghdad Tacuinum sanitatis the Arabic original and most of the Latin copies, are in tabular format 1018 – 1087 – Michael Psellos or Psellus a Byzantine monk, writer, philosopher, politician and historian. several books on medicine c. 1030 – Avicenna The Canon of Medicine The Canon remains a standard textbook in Muslim and European universities until the 18th century. c. 1071 – 1078 – Simeon Seth or Symeon Seth an 11th-century Jewish Byzantine translates Arabic works into Greek 1084 – First documented hospital in England Canterbury d. 1087 – Constantine the African 1083 – 1153 – Anna Komnene, Latinized as Comnena 1095 – Congregation of the Antonines, is founded to treat victims of "St. Anthony's fire" a skin disease. Late 11th or early 12th century – Trotula 1123 – St Bartholomew's Hospital founded by the court jester Rahere Augustine nuns originally cared for the patients. Mental patients were accepted along with others 1127 – Stephen of Antioch translates the work of Haly Abbas 1100 – 1161 – Avenzoar Teacher of Averroes 1170 – Rogerius Salernitanus composes his Chirurgia also known as The Surgery of Roger 1126 – 1198 – Averroes d. c. 1161 – Matthaeus Platearius

1200–1499 1203 – Innocent III organizes the hospital of Santo Spirito at Rome inspiring others all over Europe c. 1210 – 1277 – William of Saliceto, also known as Guilielmus de Saliceto 1210 – 1295 – Taddeo Alderotti – Scholastic medicine 1240 Bartholomeus Anglicus 1242 – Ibn al-Nafis suggests that the right and left ventricles of the heart are separate and discovers the pulmonary circulation and coronary circulation c. 1248 – Ibn al-Baytar writes on botany and pharmacy, studied animal anatomy and medicine veterinary medicine. 1249 – Roger Bacon writes about convex lens spectacles for treating long-sightedness 1257 – 1316 Pietro d'Abano also known as Petrus De Apono or Aponensis 1260 – Louis IX establishes Les Quinze-vingt; originally a retreat for the blind, it became a hospital for eye diseases, and is now one of the most important medical centers in Paris c. 1260 – 1320 Henri de Mondeville 1284 – Mansur hospital of Cairo c. 1275 – c. 1328 Joannes Zacharias Actuarius a Byzantine physician writes the last great compendium of Byzantine medicine 1275 –1326 – Mondino de Luzzi "Mundinus" carries out the first systematic human dissections since Herophilus of Chalcedon and Erasistratus of Ceos 1500 years earlier. 1288 – The hospital of Santa Maria Nuova founded in Florence, it is a strictly medical one. 1300 – concave lens spectacles to treat myopia developes in Italy. 1310 – Pietro d'Abano's Conciliator (c. 1310) d. 1348 – Gentile da Foligno 1292–1350 – Ibn Qayyim al-Jawziya 1306–1390 – John of Arderne d. 1368 – Guy de Chauliac f. 1460 – Heinrich von Pfolspeundt 1443 – 1502 – Antonio Benivieni Pathological anatomy 1493 – 1541 – Paracelsus On the relationship between medicine and surgery surgery book

1500–1699

Early 16th century: Paracelsus, an alchemist by trade, rejects occultism and pioneers the use of chemicals and minerals in medicine. Burns the books of Avicenna, Galen and Hippocrates. Hieronymus Fabricius His "Surgery" is mostly that of Celsus, Paul of Aegina, and Abulcasis citing them by name. Caspar Stromayr 1500? – 1561 Pierre Franco Ambroise Paré (1510–1590) pioneers the treatment of gunshot wounds. Bartholomeo Maggi at Bologna, Felix Wurtz of Zurich, Léonard Botal in Paris, and the Englishman Thomas Gale (surgeon), (the diversity of their geographical origins attests to the widespread interest of surgeons in the problem), all published works urging similar treatment to Paré's. But it was Paré's writings which were the most influential. 1518 – College of Physicians founded, now known as Royal College of Physicians of London is a British professional body of doctors of general medicine and its subspecialties. It received the royal charter in 1518 1510 – 1590 – Ambroise Paré surgeon 1540 – 1604 – William Clowes – Surgical chest for military surgeons 1543 – Andreas Vesalius publishes De Fabrica Corporis Humani which corrects Greek medical errors and revolutionizes European medicine 1546 – Girolamo Fracastoro proposes that epidemic diseases are caused by transferable seedlike entities 1550 – 1612 – Peter Lowe 1553 – Miguel Servet describes the circulation of blood through the lungs. 1556 – Amato Lusitano describes venous valves in the Ázigos vein 1559 – Realdo Colombo describes the circulation of blood through the lungs in detail 1563 – Garcia de Orta founds tropical medicine with his treatise on Indian diseases and treatments 1570 – 1643 – John Woodall Ship surgeons use lemon juice to treat scurvy wrote "The Surgions Mate" 1590 – Microscope is invented, which played a huge part in medical advancement 1596 – Li Shizhen publishes Běncǎo Gāngmù or Compendium of Materia Medica 1603 – Girolamo Fabrici studies leg veins and notices that they have valves which allow blood to flow only toward the heart 1621 – 1676 – Richard Wiseman 1628 – William Harvey explains the circulatory system in Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus 1665 – Robert Hooke identifies and names cells after observing them in cork under a microscope, although he did not identify their connection to life. 1683 – 1758 – Lorenz Heister 1688 – 1752 – William Cheselden

18th century 1701 – Giacomo Pylarini gives the first smallpox inoculations in Europe. They have been widely practised in the East before then. 1714 – 1789 – Percivall Pott 1720 – Lady Mary Wortley Montagu 1728 – 1793 – John Hunter 1736 – Claudius Aymand performs the first successful appendectomy 1744 – 1795 – Pierre-Joseph Desault First surgical periodical 1747 – James Lind discovers that citrus fruits prevent scurvy 1749 – 1806 – Benjamin Bell – Leading surgeon of his time and father of a surgical dynasty, author of "A System of Surgery" 1752 – 1832 – Antonio Scarpa 1763 – 1820 – John Bell 1766 – 1842 – Dominique Jean Larrey Surgeon to Napoleon 1768 – 1843 – Astley Cooper surgeon lectures principles and practice 1774 – 1842 – Charles Bell, surgeon 1774 – Joseph Priestley discovers nitrous oxide, nitric oxide, ammonia, hydrogen chloride and oxygen 1777 – 1835 – Baron Guillaume Dupuytren – Head surgeon at Hôtel-Dieu de Paris, The age Dupuytren 1785 – William Withering publishes "An Account of the Foxglove" the first systematic description of digitalis in treating dropsy 1790 – Samuel Hahnemann rages against the prevalent practice of bloodletting as a universal cure and founds homeopathy 1796 – Edward Jenner develops a smallpox vaccination method 1799 – Humphry Davy discovers the anesthetic properties of nitrous oxide

19th century 1800 – Humphry Davy announces the anaesthetic properties of nitrous oxide. 1803 – 1841 – Morphine was first isolated by Friedrich Sertürner, this is generally believed to be the first isolation of an active ingredient from a plant. 1813–1883 – James Marion Sims vesico-vaganial surgery Father of surgical gynecology. 1816 – René Laennec invents the stethoscope. 1827 – 1912 – Joseph Lister antiseptic surgery Father of modern surgery 1818 – James Blundell performs the first successful human transfusion. 1842 – Crawford Long performs the first surgical operation using anesthesia with ether. 1845 – John Hughes Bennett first describes leukemia as a blood disorder. 1846 – First painless surgery with general anesthetic. 1847 – Ignaz Semmelweis discovers how to prevent puerperal fever. 1849 – Elizabeth Blackwell is the first woman to gain a medical degree in the United States. 1850 – Female Medical College of Pennsylvania (later Woman's Medical College), the first medical college in the world to grant degrees to women, is founded in Philadelphia. 1858 – Rudolf Carl Virchow 13 October 1821 – 5 September 1902 his theories of cellular pathology spelled the end of Humoral medicine. 1861 – Louis Pasteur discovers the germ theory of disease. 1861 – Snellen chart developed by Herman Snellen. 1867 – Lister publishes Antiseptic Principle of the Practice of Surgery, based partly on Pasteur's work. 1870 – Louis Pasteur and Robert Koch establish the germ theory of disease. 1878 – Ellis Reynolds Shipp graduates from the Women's Medical College of Pennsylvania and begins practice in Utah. 1879 – First vaccine for cholera. 1881 – Louis Pasteur develops an anthrax vaccine. 1882 – Louis Pasteur develops a rabies vaccine. 1887 – Willem Einthoven invents electrocardiography (ECG/EKG) 1890 – Emil von Behring discovers antitoxins and uses them to develop tetanus and diphtheria vaccines. 1895 – Wilhelm Conrad Röntgen discovers medical use of X-rays in medical imaging

20th century

1900s 1901 – Karl Landsteiner discovers the existence of different human blood types 1901 – Alois Alzheimer identifies the first case of what becomes known as Alzheimer's disease 1906 – Frederick Hopkins suggests the existence of vitamins and suggests that a lack of vitamins causes scurvy and rickets 1907 – Paul Ehrlich develops a chemotherapeutic cure for sleeping sickness 1907 – Henry Stanley Plummer develops the first structured patient record and clinical number (Mayo clinic) 1908 – Victor Horsley and R. Clarke invents the stereotactic method 1909 – First intrauterine device described by Richard Richter. 1910 – Hans Christian Jacobaeus performs the first laparoscopy on humans

1910s 1917 – Julius Wagner-Jauregg discovers the malarial fever shock therapy for general paresis of the insane

1920s 1921 – Edward Mellanby discovers vitamin D and shows that its absence causes rickets 1921 – Frederick Banting and Charles Best discover insulin – important for the treatment of diabetes 1921 – Fidel Pagés pioneers epidural anesthesia 1923 – First vaccine for diphtheria 1924 – Hans Berger discovers human electroencephalography 1926 – First vaccine for pertussis 1927 – First vaccine for tuberculosis 1927 – First vaccine for tetanus

1930s 1930 – First successful sex reassignment surgery performed on Lili Elbe in Dresden, Germany. 1932 – Gerhard Domagk develops a chemotherapeutic cure for streptococcus 1933 – Manfred Sakel discovers insulin shock therapy 1935 – Ladislas J. Meduna discovers metrazol shock therapy 1935 – First vaccine for yellow fever 1936 – Egas Moniz discovers prefrontal lobotomy for treating mental diseases; Enrique Finochietto develops the now ubiquitous self-retaining thoracic retractor 1938 – Ugo Cerletti and Lucio Bini discover electroconvulsive therapy 1938 – Howard Florey and Ernst Chain investigate Penicillin and attempted to mass-produce it and tested it on the policeman Albert Alexander (police officer) who recovered but died due to a lack of Penicillin

1940s 1943 – Willem J. Kolff builds the first dialysis machine 1944 – Disposable catheter – David S. Sheridan 1946 – Chemotherapy – Alfred G. Gilman and Louis S. Goodman 1947 – Defibrillator – Claude Beck 1948 – Acetaminophen – Julius Axelrod, Bernard Brodie 1948 – The World Health Organization (WHO) is founded as a specialised agency of the United Nations. 1949 – First implant of intraocular lens, by Sir Harold Ridley 1949 – Mechanical assistor for anesthesia – John Emerson

1950s 1952 – Jonas Salk develops the first polio vaccine (available in 1955) 1952 – Cloning – Robert Briggs and Thomas King 1953 – First live birth from frozen sperm 1953 – Heart-lung machine – John Heysham Gibbon 1953 – Medical ultrasonography – Inge Edler 1954 – Joseph Murray performs the first human kidney transplant (on identical twins) 1954 – Ventouse – Tage Malmstrom 1955 – Tetracycline – Lloyd Conover 1956 – Metered-dose inhaler – 3M 1957 – William Grey Walter invents the brain EEG topography (toposcope) 1958 – Pacemaker – Rune Elmqvist 1959 – In vitro fertilization – Min Chueh Chang

1960s 1960 – Invention of cardiopulmonary resuscitation (CPR) 1960 – First combined oral contraceptive approved by the FDA 1962 – Hip replacement – John Charnley 1962 – Beta blocker James W. Black 1962 – Albert Sabin develops first oral polio vaccine 1963 – Artificial heart – Paul Winchell 1963 – Thomas Starzl performs the first human liver transplant 1963 – James Hardy performs the first human lung transplant 1963 – Valium (diazepam) – Leo H. Sternbach 1964 – First vaccine for measles 1965 – Frank Pantridge installs the first portable defibrillator 1965 – First commercial ultrasound 1966 – C. Walton Lillehei performs the first human pancreas transplant 1966 – Rubella Vaccine – Harry Martin Meyer and Paul D. Parkman 1967 – First vaccine for mumps 1967 – René Favaloro develops Coronary Bypass surgery 1967 – Christiaan Barnard performs the first human heart transplant 1968 – Powered prothesis – Samuel Alderson 1968 – Controlled drug delivery – Alejandro Zaffaron 1969 – Balloon catheter – Thomas Fogarty 1969 – Cochlear implant – William House

1970s

1970 – Cyclosporine, the first effective immunosuppressive drug is introduced in organ transplant practice 1971 – MMR Vaccine – developed by Maurice Hilleman 1971 – Genetically modified organisms – Ananda Chakrabart 1971 – Magnetic resonance imaging – Raymond Vahan Damadian 1971 – Computed tomography (CT or CAT Scan) – Godfrey Hounsfield 1971 – Transdermal patches – Alejandro Zaffaroni 1971 – Sir Godfrey Hounsfield invents the first commercial CT scanner 1972 – Insulin pump Dean Kamen 1973 – Laser eye surgery (LASIK) – Mani Lal Bhaumik 1974 – Liposuction – Giorgio Fischer 1976 – First commercial PET scanner 1978 – First live birth from in vitro fertilisation (IVF) 1978 – Last fatal case of smallpox 1979 – Antiviral drugs – George Hitchings and Gertrude Elion

1980s

1980 – Smallpox is declared eradicated by the WHO. 1980 – Raymond Damadian builds first commercial MRI scanner 1980 – Lithotripter – Dornier Research Group 1980 – First vaccine for hepatitis B – Baruch Samuel Blumberg 1980 – Cloning of interferons – Sidney Pestka 1981 – Artificial skin – John F. Burke and Ioannis V. Yannas 1981 – Bruce Reitz performs the first human heart-lung combined transplant 1982 – Human insulin – Eli Lilly 1982 – Willem Johan Kolff performs the first artificial heart transplant. 1985 – Automated DNA sequencer – Leroy Hood and Lloyd Smith 1985 – Polymerase chain reaction (PCR) – Kary Mullis 1985 – Surgical robot – Yik San Kwoh 1985 – DNA fingerprinting – Alec Jeffreys 1985 – Capsule endoscopy – Tarun Mullick 1986 – Fluoxetine HCl – Eli Lilly and Co 1987 – commercially available Statins – Merck & Co. 1987 – Tissue engineering – Joseph Vacanti & Robert Langer 1988 – Intravascular stent – Julio Palmaz 1988 – Laser cataract surgery – Patricia Bath 1989 – Pre-implantation genetic diagnosis (PGD) – Alan Handyside 1989 – DNA microarray – Stephen Fodor

1990s

1990 – Gamow bag® – Igor Gamow 1992 – Description of Brugada syndrome (Pedro and Josep Brugada) 1992 – First vaccine for hepatitis A available 1992 – Electroactive polymers (artificial muscle) – SRI International 1992 – Intracytoplasmic sperm injection (ICSI) – Andre van Steirteghem 1995 – Adult stem cell use in regeneration of tissues and organs in vivo – B. G Matapurkar U.S . International Patent 1996 – Dolly the Sheep cloned 1998 – Stem cell therapy – James Thomson 1999 – The hormone Ghrelin is identified by Japanese scientists Masayasu Kojima, Kenji Kangawa and their colleagues.

21st century

2000s

2000 – The Human Genome Project draft was completed. 2001 – The first telesurgery was performed by Jacques Marescaux. 2003 – Carlo Urbani, of Doctors without Borders alerted the World Health Organization to the threat of the SARS virus, triggering the most effective response to an epidemic in history. Urbani succumbs to the disease himself in less than a month. 2005 – Jean-Michel Dubernard performs the first partial face transplant. 2006 – First HPV vaccine approved. 2006 – The second rotavirus vaccine approved (first was withdrawn). 2007 – The visual prosthetic (bionic eye) Argus II. 2008 – Laurent Lantieri performs the first full face transplant.

2010s

2011 – First successful Uterus transplant from a deceased donor in Turkey 2013 – The first kidney grown in vitro in the U.S. 2013 – The first human liver was grown from stem cells in Japan. 2014 – A 3D printer is used for first ever skull transplant. 2014 - Sonendo, a medical technology company based in Laguna Hills, California, introduces the GentleWave system in the United States for root canal treatments. 2016 – The first ever artificial pancreas was created 2019 – 3D-print heart from human patient's cells.

2020s

2020 – First vaccine for COVID-19. 2022 – The complete human genome is sequenced.

See also Timeline of antibiotics Timeline of vaccines Timeline of hospitals

Notes

Citations

Reference:

1. International patent USA. .wef 1995. US PTO no.6227202 and 20020007223. 2. R. Maingot's Text Book of Abdominal operations.1997 USA. 3. Text book of Obstetrics and Gynecology. 2010 J P Publishers.

References Matapurkar B G. (1995). US international Patent 6227202 and 20020007223.medical use of Adult Stem cells. A new physiological phenomenon of Desired Metaplasia for regeneration of tissues and organs in vivo. Annals of NYAS 1998.

Bynum, W. F. and Roy Porter, eds. Companion Encyclopedia of the History of Medicine (2 vol. 1997); 1840pp; 72 long essays by scholars excerpt and text search Conrad, Lawrence I. et al. The Western Medical Tradition: 800 BC to AD 1800 (1995); excerpt and text search Bynum, W.F. et al. The Western Medical Tradition: 1800–2000 (2006) excerpt and text search Loudon, Irvine, ed. Western Medicine: An Illustrated History (1997) online Archived 26 September 2017 at the Wayback Machine McGrew, Roderick. Encyclopedia of Medical History (1985) Porter, Roy (1997). The Greatest Benefit to Mankind: A Medical History of Humanity from Antiquity to the Present. Harper Collins. ISBN 0-00-215173-1. Porter, Roy, ed. The Cambridge History of Medicine (2006); 416pp; excerpt and text search Porter, Roy, ed. The Cambridge Illustrated History of Medicine (2001) excerpt and text search excerpt and text search Singer, Charles, and E. Ashworth Underwood. A Short History of Medicine (2nd ed. 1962) Watts, Sheldon. Disease and Medicine in World History (2003), 166pp online Archived 26 September 2017 at the Wayback Machine

Further reading Allbutt, Thomas Clifford (1911). "Medicine" . In Chisholm, Hugh (ed.). Encyclopædia Britannica. Vol. 18 (11th ed.). Cambridge University Press.

External links Interactive timeline of medicine and medical technology (requires Flash plugin) The Historyscoper

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