In enzymology, a trans-epoxysuccinate hydrolase (EC 3.3.2.4) is an enzyme that catalyzes the chemical reaction
trans-2,3-epoxysuccinate + H2O ⇌ {\displaystyle \rightleftharpoons } meso-tartrate Thus, the two substrates of this enzyme are trans-2,3-epoxysuccinate and H2O, whereas its product is meso-tartrate. This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is trans-2,3-epoxysuccinate hydrolase. Other names in common use include trans-epoxysuccinate hydratase, and tartrate epoxydase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
Allen RH, Jakoby WB (1969). "Tartaric acid metabolism. IX. Synthesis with tartrate epoxidase". J. Biol. Chem. 244 (8): 2078–84. doi:10.1016/S0021-9258(18)94369-3. PMID 5782001.
