astronomy

Trese Leinders-Zufall

Trese Leinders-Zufall is a astronomy topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Trese Leinders-Zufall rather than just read about it. In short: Trese Leinders-Zufall née Leinders (born January 19, 1963) is a Dutch physiologist and professor at the Center for Integrative Physiology and Molecular Medicine at the Saarland University, Germany. She is a faculty member in the Department of Physiology at the Faculty of Medicine.

Key takeaways

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Reference excerpt

Trese Leinders-Zufall née Leinders (born January 19, 1963) is a Dutch physiologist and professor at the Center for Integrative Physiology and Molecular Medicine at the Saarland University, Germany. She is a faculty member in the Department of Physiology at the Faculty of Medicine. She is known for her research investigating the olfactory system. Her work focuses on the mechanisms of odor and pathogen perception, the neural pathways that mediate olfactory-encoded social behaviors, and the function of TRP channels in the neurons of the olfactory, respiratory, and central nervous systems.

Education and career Leinders-Zufall received her first training in Biology at the Utrecht University in the Netherlands, and earned her degree in 1992. She was a postdoctoral fellow and later an associate research scientist at Yale University from 1992 until 1997 in the Department of Neurology (Stephen G. Waxman) and the Department of Neurobiology (Gordon M. Shepherd). Leinders-Zufall accepted a position of assistant professor at University of Maryland, Baltimore in 1997, and was promoted to associate professor in 2002. In 2008 she received an endowed Lichtenberg Professorship from the Volkswagen Foundation in Germany, and accepted a full professorship at the Department of Physiology, Saarland University, Campus Homburg, where the School of Medicine is located. This endowed professorship has allowed her to establish an internationally recognized research program in Germany, positioned at the interface between the nervous-, endocrine- and immune systems.

Research Leinders-Zufall is known for her work on olfactory systems, neural pathways mediating olfactory-encoded innate social behaviors, and investigations into various TRP channel subtypes. Early in her career, she studied calcium-activated potassium channels. Leinders-Zufall mainly studies the basic molecular and cellular processes that allow animals to communicate through chemicals. She studies the mechanisms that control complex behaviors, such as aggression, parental care, and reproduction. Her main focus is on signal transduction cascades and ion channels that are controlled by second messengers. She uses many different advanced methods in electrophysiology, calcium imaging, and photopharmacology. A series of fundamental studies of odor transduction was produced by the combined effort of Gordon M. Shepherd, Stuart Firestein, Frank Zufall, Charles A. Greer and Trese Leinders-Zufall: "This included inhibition of the CNG channels by intracellular calcium, and modulation of the CNG channels by carbon monoxide and by cyclic GMP." Then, Leinders-Zufall went on to identify odor-induced calcium transients in single olfactory cilia. Leinders-Zufall's research has contributed significantly to our understanding of the mechanisms underlying chemosensation (exteroception) and interoception, and of the connections between these mechanisms and the nervous system.

Awards and honors Erasmus-stipend, European Community (NUFFIC) (1988) Takasago Award for Research in Olfaction (2002) Endowed Lichtenberg Professorship (Volkswagen Foundation, Hannover, Germany) (2007)

Key papers Leinders-Zufall, Trese; Greer, Charles A.; Shepherd, Gordon M.; Zufall, Frank (1998-08-1) "Imaging odor-induced calcium transients in single olfactory cilia: specificity of activation and role in transduction". J Neurosci. 18 (15):5630-9. PMID 9671654 doi:10.1523/JNEUROSCI.18-15-05630.1998 Leinders-Zufall, Trese; Lane, Andrew P.; Puche, Adam C.; Ma, Weidong; Novotny, Milos V.; Shipley, Michael T.; Zufall, Frank (2000-06-15). "Ultrasensitive pheromone detection by mammalian vomeronasal neurons". Nature. 405 (6788): 792–796. Bibcode:2000Natur.405..792L. doi:10.1038/35015572. ISSN 0028-0836. PMID 10866200. Leypold, Bradley G.; Yu, C. Ron; Leinders-Zufall, Trese; Kim Michelle M.; Zufall, Frank; Axel, Richard (2002-04-23) Altered sexual and social behaviors in trp2 mutant mice. Proc Natl Acad Sci U S A. 99 (9):6376-81. PMID 11972034 DOI:10.1073/pnas.082127599 Müller, Markus; Niemeyer, Konstantin; Ojha, Navin K.; Porav, Sebastian A.; Vinayagam, Deivanayagabarathy.; Urban, Nicole; Büchau, Fanny; Oleinikov, Katharina; Makke, Mazze; Bauer, Claudia C.; Johnson, Aidan V.; Muench, Stephen P.; Zufall, Frank; Bruns, Dieter; Schwarz, Yvonne; Raunser, Stefan; Leinders-Zufall, Trese; Bon, Robin S.; Schaefer, Michael; Thorn-Seshold, Oliver (2026-01-16) Ideal efficacy photoswitches for chemocontrol of TRPC4/5 channel functions in live tissues. Nature Chem Biol. 22 (2):180-191. PMID 41545580 doi:10.1038/s41589-025-02085-x

References

External links Trese Leinders-Zufall publications indexed by Google Scholar

Illustrations

Worked examples

Example 1 — a first encounter with Trese Leinders-Zufall

Start with the simplest possible case. Write down what Trese Leinders-Zufall claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In astronomy, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Trese Leinders-Zufall before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Trese Leinders-Zufall ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Trese Leinders-Zufall

In research: Trese Leinders-Zufall appears in astronomy research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Trese Leinders-Zufall in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Trese Leinders-Zufall is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1963 births, 21st-century women biologists, Academic staff of Saarland University, so understanding it makes those chapters shorter.
In everyday life: Look for Trese Leinders-Zufall outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Trese Leinders-Zufall in 20 minutes

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Frequently asked questions

What is Trese Leinders-Zufall in simple terms?

Why does Trese Leinders-Zufall matter?

Because it connects several astronomy ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Trese Leinders-Zufall?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Trese Leinders-Zufall.