Trifluoroacetyl fluoride is an organic compound of fluorine, oxygen, and carbon with the chemical formula C2F4O. The compound belongs to the group of carboxylic acid fluorides, specifically the fluoride of trifluoroacetic acid.
Synthesis Trifluoroacetyl fluoride can be prepared by the reaction of trifluoroacetic anhydride and anhydrous hydrogen fluoride:
(CF3CO)2O + HF → CF3COF + CF3COOH or by the reaction of trifluoroacetic acid and vanadium pentafluoride:
CF3COOH + VF5 → VOF3 + HF + CF3COF↑
Chemical properties Trifluoroacetyl fluoride can react with rubidium fluoride or cesium fluoride in acetonitrile to form the corresponding pentafluoroethanolate:
CF3COF + MF → CF3CF2OM (M = Rb, Cs) The compound reacts with sulfur trioxide to form trifluoroacetyl fluorosulfonate:
CF3COF + SO3 → CF3C(O)OSO2F The compound hydrolyses in water.
Uses Trifluoroacetyl fluoride is an important industrial intermediate for trifluoroacetic acid, which is produced by its hydrolysis.
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