biology

U. C. Chaturvedi

U. C. Chaturvedi is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand U. C. Chaturvedi rather than just read about it. In short: Umesh Chandra Chaturvedi (2 March 1939 – 28 December 2021) was an Indian virologist, immunologist, medical microbiologist, CSIR Emeritus Scientist and a former chairman of the Bharat Immunologicals and Biologicals Corporation. The founder head of the department of microbiology at King George's Medical University, he is known for his studies on Dengue virus infection.

Key takeaways

U. C. Chaturvedi belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect U. C. Chaturvedi to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of U. C. Chaturvedi from memory before moving on to harder problems.

Reference excerpt

Umesh Chandra Chaturvedi (2 March 1939 – 28 December 2021) was an Indian virologist, immunologist, medical microbiologist, CSIR Emeritus Scientist and a former chairman of the Bharat Immunologicals and Biologicals Corporation. The founder head of the department of microbiology at King George's Medical University, he is known for his studies on Dengue virus infection. Chaturvedi is an elected fellow of all the three major Indian science academies viz. Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy as well as the Royal College of Pathologists and National Academy of Medical Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1981.

Biography U. C. Chaturvedi, born on 2 March 1939 at the Unnao, an industrial city in the Indian state of Uttar Pradesh to Chandra and Satya Prakash Chaturvedi, completed his early college education at Government Inter College, Etawah in 1956, before graduating in medicine from King George's Medical University (then known as King George's Medical College) in 1961. Subsequently, he joined KGMU as a research assistant cum demonstrator and became a full faculty member in 1964. During this time, he pursued his higher studies at the institution and earned an MD in Pathology and Bacteriology in 1965. He spent the rest of his regular career at KGMU till his superannuation in 1999 during which time he rose through ranks holding the positions of a lecturer (1964–65 and 1967), reader (1967–84) and a professor (1984–99). In between, he took a sabbatical during 1965 to 1967 and worked as an ICMR Senior Research Fellow at National Institute of Virology under the guidance of T. Ramchandra Rao, as a Senior Medical Commonwealth Fellow with Thomas Henry Flewett and Peter Wildy at University of Birmingham and as an Alexander von Humboldt Fellow at the laboratory of F. Lehmann-Grube at University of Hamburg. Post-retirement, he served at the Faculty of Medicine of Kuwait University and on his return to India, became associated with Indian Institute of Toxicology Research (then known as Industrial Toxicology Research Centre) in Lucknow where he continued his researches as an emeritus scientist of the Council of Scientific and Industrial Research. Subsequently, he chaired Bharat Immunologicals and Biologicals Corporation, (BIBCOL) a Government of India undertaking involved in the manufacture of oral Polio vaccines, Zinc tablets and kits for the management of Diarrhea. He served BIBCOL till 2006 when he was succeeded by Virander Singh Chauhan. Chaturvedi is married to Uma and the couple has two daughters, Preeti and Pratibha and a son, Jai Deep. The family lives in Lucknow in Uttar Pradesh.

Legacy

Chaturvedi's early researches spanned the pathogenesis of various diseases which he carried out using animal models and subsequently reconfirming them by clinical trials. The human disorders he covered included chromium toxicity, immunological cardiac injury and dengue haemorrhagic fever (DHF) and it was during this time, he demonstrated that T-lymphocytes could inflict damage on heart tissues thereby leading to post-myocardial infarction and the postpericardiotomy syndrome. When an epidemic of dengue broke out in Kanpur in 1968, the team led by him carried out extensive studies independently and were successful in isolating dengue virus from the patients for further investigations. With the help of his studies on the pathogenesis of Dengue fever, he demonstrated that T helper cell-Type II cytokine receptor causes severity of the disease and he termed the incidence as Cytokine Tsunami, as revealed in articles and an editorial written by him in Indian Journal of Medical Research. Chaturvedi elucidated the pathogenesis of dengue fever by proposing how virus-infected macrophages incited cytotoxic factor (CF) production in CD4+ T cells which accelerated production of free radicals, nitrite, reactive oxygen and peroxynitrite. He developed an in-vitro model for testing metal toxicity and prescribed pre-treatment protocols using chromium picolinate which countered the incidence of thrombocytopenia induced by the virus. His studies have widened the understanding of Dengue Haemorrhagic Fever and associated Shock Syndrome. He has documented his researches by way of over 255 articles in per-reviewed journals and the online article repository of the Indian Academy of Sciences has listed 216 of them. Besides, he has contributed chapters to books published by others and his work has been cited by a number of authors and researchers. He has also delivered invited or keynote speeches and has guided a number of master's and doctoral scholars in their studies. On the academic front, he was the founder head of the Department of Microbiology at King George Medical College and his contributions have been reported in the establishment of a viral diagnostic laboratory at Aligarh Muslim University. He has been associated with many Government of India agencies such as Indian Council of Medical Research, Department of Science and Technology, Department of Biotechnology and the Council of Scientific and Industrial Research and sat in the Scientific Advisory Committee of the National AIDS Research Institute during 2003–04. He has been a member of the Task Force on Infectious Disease Biology of the Department of Biotechnology and represented India in the General Assembly of the International Federation of Tropical Medicine during 1984–85. He sat in the council of the Indian Immunology Society (1992–94) and was the secretary of the Indian Association Medical Microbiologists for three terms (1983, 84 and 1985). He held the position of a treasurer of the Indian Association of Pathologists and Microbiologists from 1976 to 1980 and served as its president in 1988. He has also served as a member of the editorial boards of African Journal of Clinical and Experimental Immunology, Indian Journal of Medical Research and the Indian Journal of Medical Microbiology and has served as the peer reviewer of Dengue Bulletin, published by the South-East Asia Regional Office (SEARO) of the World Health Organization. Chaturvedi died on 28 December 2021, at the age of 82.

… excerpt ends here. Continue reading the full article.

Illustrations

Worked examples

Example 1 — a first encounter with U. C. Chaturvedi

Start with the simplest possible case. Write down what U. C. Chaturvedi claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to U. C. Chaturvedi before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about U. C. Chaturvedi ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of U. C. Chaturvedi

In research: U. C. Chaturvedi appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses U. C. Chaturvedi in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: U. C. Chaturvedi is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1939 births, 2021 deaths, 20th-century Indian biologists, so understanding it makes those chapters shorter.
In everyday life: Look for U. C. Chaturvedi outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study U. C. Chaturvedi in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what U. C. Chaturvedi means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain U. C. Chaturvedi out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is U. C. Chaturvedi in simple terms?

Why does U. C. Chaturvedi matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study U. C. Chaturvedi?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on U. C. Chaturvedi.