engineering

UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase

UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase rather than just read about it. In short: In enzymology, an UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase (EC 2.3.2.10) is an enzyme that catalyzes the chemical reaction It was named following the Enzyme Commission number by the IUBMB nomenclature committee L-alanyl-tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine ⇌ {\displaystyle \rightleftharpoons } tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-ly…

Key takeaways

UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase from memory before moving on to harder problems.

Reference excerpt

In enzymology, an UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase (EC 2.3.2.10) is an enzyme that catalyzes the chemical reaction It was named following the Enzyme Commission number by the IUBMB nomenclature committee

L-alanyl-tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine ⇌ {\displaystyle \rightleftharpoons } tRNA + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D- alanyl-D-alanine Thus, the two substrates of this enzyme are L-alanyl-tRNA and UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine, whereas its 3 products are tRNA, UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-, and alanyl-D-alanine. This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-ala nyl-D-alanine N6-alanyltransferase. Other names in common use include alanyl-transfer ribonucleate-uridine, diphosphoacetylmuramoylpentapeptide transferase, UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase, uridine diphosphoacetylmuramoylpentapeptide lysine, N6-alanyltransferase, L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-, and alanyl-D-alanine 6-N-alanyltransferase. This enzyme participates in peptidoglycan biosynthesis.

Structural studies As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1P4N, PDB: 1XE4, PDB: 1XF8, and PDB: 1XIX.

References

Plapp R, Strominger JL (1970). "Biosynthesis of the peptidoglycan of bacterial cell walls. 18 Purification and properties of L-alanyl transfer ribonucleic acid-uridine diphosphate-N-acetylmuramyl-pentapeptide transferase from Lactobacillus viridescens". J. Biol. Chem. 245 (14): 3675–82. doi:10.1016/S0021-9258(18)62979-5. PMID 4248527.

Worked examples

Example 1 — a first encounter with UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase

Start with the simplest possible case. Write down what UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase

In research: UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.3.2, EC 2.3 stubs, Enzymes of known structure, so understanding it makes those chapters shorter.
In everyday life: Look for UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase in simple terms?

Why does UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase.