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UNC13D

UNC13D is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand UNC13D rather than just read about it. In short: Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the UNC13D gene. Function Munc13-4 is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.

UNC13D — main illustration
UNC13D — illustration

Key takeaways

  • UNC13D belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect UNC13D to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of UNC13D from memory before moving on to harder problems.

Reference excerpt

Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the UNC13D gene.

Function Munc13-4 is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.

Clinical significance Mutations in the UNC13D gene are associated with hemophagocytic lymphohistiocytosis type 3.

References

Further reading

External links UNC13D+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Illustrations

UNC13D illustration
UNC13D illustration
UNC13D illustration
UNC13D illustration

Worked examples

Example 1 — a first encounter with UNC13D

Start with the simplest possible case. Write down what UNC13D claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to UNC13D before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about UNC13D ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of UNC13D

In research
UNC13D appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses UNC13D in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
UNC13D is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 17, Human chromosome 17 gene stubs, so understanding it makes those chapters shorter.
In everyday life
Look for UNC13D outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study UNC13D in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what UNC13D means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain UNC13D out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is UNC13D in simple terms?

Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the UNC13D gene. Function Munc13-4 is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc…

Why does UNC13D matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study UNC13D?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on UNC13D.

Tags

  • Genes on human chromosome 17
  • Human chromosome 17 gene stubs

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