In enzymology, an UTP—xylose-1-phosphate uridylyltransferase (EC 2.7.7.11) is an enzyme that catalyzes the chemical reaction
UTP + alpha-D-xylose 1-phosphate ⇌ {\displaystyle \rightleftharpoons } diphosphate + UDP-xylose Thus, the two substrates of this enzyme are UTP and alpha-D-xylose 1-phosphate, whereas its two products are diphosphate and UDP-xylose. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:alpha-D-xylose-1-phosphate uridylyltransferase. Other names in common use include xylose-1-phosphate uridylyltransferase, uridylyltransferase, xylose 1-phosphate, UDP-xylose pyrophosphorylase, uridine diphosphoxylose pyrophosphorylase, and xylose 1-phosphate uridylyltransferase. This enzyme participates in nucleotide sugars metabolism.
References
Ginsburg V, Neufeld EF, Hassid WZ (1956). "Enzymatic Synthesis of Uridine Diphosphate Xylose and Uridine Diphosphate Arabinose". Proc. Natl. Acad. Sci. U.S.A. 42 (6): 333–5. Bibcode:1956PNAS...42..333G. doi:10.1073/pnas.42.6.333. PMC 528284. PMID 16578456.
