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biology

UVSSA

UVSSA is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand UVSSA rather than just read about it. In short: UV-stimulated scaffold protein A is a protein that in humans that is encoded by the UVSSA gene (previously KIAA1530). This protein is involved in DNA repair in response to UV radiation damage.

UVSSA — main illustration
UVSSA — illustration

Key takeaways

  • UVSSA belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect UVSSA to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of UVSSA from memory before moving on to harder problems.

Reference excerpt

UV-stimulated scaffold protein A is a protein that in humans that is encoded by the UVSSA gene (previously KIAA1530). This protein is involved in DNA repair in response to UV radiation damage. In particular, it interacts with nucleotide excision repair proteins (specifically TC-NER subunits) along with RNA polymerase II subunits that have stalled. Mutations in this gene have been identified to cause the UV-sensitive syndrome and recently, its important role in Transcription-coupled repair has been identified.

Clinical relevance Mutations in this gene cause UV-sensitive syndrome.

References

Further reading

Illustrations

UVSSA illustration
UVSSA illustration
UVSSA illustration
UVSSA illustration

Worked examples

Example 1 — a first encounter with UVSSA

Start with the simplest possible case. Write down what UVSSA claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to UVSSA before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about UVSSA ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of UVSSA

In research
UVSSA appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses UVSSA in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
UVSSA is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 4, Human chromosome 4 gene stubs, so understanding it makes those chapters shorter.
In everyday life
Look for UVSSA outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study UVSSA in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what UVSSA means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain UVSSA out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is UVSSA in simple terms?

UV-stimulated scaffold protein A is a protein that in humans that is encoded by the UVSSA gene (previously KIAA1530). This protein is involved in DNA repair in response to UV radiation damage.

Why does UVSSA matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study UVSSA?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on UVSSA.

Tags

  • Genes on human chromosome 4
  • Human chromosome 4 gene stubs

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