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Wikipedia

VK2809

VK2809

VK2809 (formerly known as MB07811) is a thyromimetic prodrug whose active form is selective for the THR-β isoform. It is being developed by Viking Therapeutics in a phase II trial for the treatment of nonalcoholic steatohepatitis and is also being investigated for glycogen storage disease type Ia. In 2023, Viking Therapeutics filed a lawsuit against the developer of ASC41, Chinese company Ascletis BioScience, accusing it of stealing Viking's trade secrets to develop ASC41 which is allegedly similar to, or identical to, VK2809.

References

Tags

  • 3-Chlorophenyl compounds
  • Dioxaphosphorinanes
  • Experimental drugs developed for non-alcoholic fatty liver disease
  • Isopropyl compounds
  • Phenols
  • Prodrugs
  • Thyroid hormone receptor beta agonists