biology

VMA22

VMA22 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand VMA22 rather than just read about it. In short: Vacuolar ATPase assembly protein VMA22 is a protein that in humans is encoded by the VMA22 gene (formerly CCDC115). Function The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells.

Key takeaways

VMA22 belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect VMA22 to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of VMA22 from memory before moving on to harder problems.

Reference excerpt

Vacuolar ATPase assembly protein VMA22 is a protein that in humans is encoded by the VMA22 gene (formerly CCDC115).

Function The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans. [provided by RefSeq, Mar 2016].

References

Illustrations

Worked examples

Example 1 — a first encounter with VMA22

Start with the simplest possible case. Write down what VMA22 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to VMA22 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about VMA22 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of VMA22

In research: VMA22 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses VMA22 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: VMA22 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 2, Human chromosome 2 gene stubs, so understanding it makes those chapters shorter.
In everyday life: Look for VMA22 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study VMA22 in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what VMA22 means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain VMA22 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is VMA22 in simple terms?

Vacuolar ATPase assembly protein VMA22 is a protein that in humans is encoded by the VMA22 gene (formerly CCDC115). Function The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesi…

Why does VMA22 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study VMA22?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on VMA22.