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biology

VPS13A

VPS13A is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand VPS13A rather than just read about it. In short: VPS13A (Vacuolar protein sorting-associated protein 13A) is a protein that in humans is encoded by the VPS13A gene. Function The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane.

VPS13A — main illustration
VPS13A — illustration

Key takeaways

  • VPS13A belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect VPS13A to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of VPS13A from memory before moving on to harder problems.

Reference excerpt

VPS13A (Vacuolar protein sorting-associated protein 13A) is a protein that in humans is encoded by the VPS13A gene.

Function The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder, chorea acanthocytosis. Alternative splicing of this gene results in multiple transcript variants.

References

Further reading

External links GeneReviews/NCBI/NIH/UW entry on Chorea-acanthocytosis

Illustrations

VPS13A illustration
VPS13A illustration
VPS13A illustration
VPS13A illustration
VPS13A illustration

Worked examples

Example 1 — a first encounter with VPS13A

Start with the simplest possible case. Write down what VPS13A claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to VPS13A before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about VPS13A ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of VPS13A

In research
VPS13A appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses VPS13A in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
VPS13A is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 9, Human chromosome 9 gene stubs, so understanding it makes those chapters shorter.
In everyday life
Look for VPS13A outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study VPS13A in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what VPS13A means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain VPS13A out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is VPS13A in simple terms?

VPS13A (Vacuolar protein sorting-associated protein 13A) is a protein that in humans is encoded by the VPS13A gene. Function The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane.

Why does VPS13A matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study VPS13A?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on VPS13A.

Tags

  • Genes on human chromosome 9
  • Human chromosome 9 gene stubs

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