Venenatine is an indole alkaloid that was first isolated from Alstonia venenata in 1964. It is also found in A. macrophylla and A. scholaris. It appears to have antifungal properties and has been synthesized. Venenatine inhibits the p300 histone acetyltransferase enzyme.
References
Further reading Bhattacharya SK, Ray AB, Dutta SC (1975). "Psychopharmacological investigations of the 4-methoxyindole alkaloids of Alstonia venenata". Planta Medica. 27 (2): 164–170. Bibcode:1975PlMed..27..164B. doi:10.1055/s-0028-1097779. PMID 1121530. Dhawan BN (25 January 1995). "Research properties in natural products having CNS effects". Current Science. 68 (2): 202–204. JSTOR 24096503.


