Verrucomicrobiota is a phylum of Gram-negative bacteria that contains only a few described species. The species identified have been isolated from fresh water, marine and soil environments and human faeces. A number of as-yet uncultivated species have been identified in association with eukaryotic hosts including extrusive explosive ectosymbionts of protists and endosymbionts of nematodes from genus Xiphinema, residing in their gametes. The verrucomicrobial bacterium Akkermansia muciniphila is a human intestinal symbiotic bacterium that is considered as a promising probiotic. Verrucomicrobiota are abundant within the environment, though relatively inactive. This phylum is considered to have two sister phyla: Chlamydiota (formerly Chlamydiae) and Lentisphaerota (formerly Lentisphaerae) within the PVC superphylum. The Verrucomicrobiota phylum can be distinguished from neighbouring phyla within the PVC group by the presence of several conserved signature indels (CSIs). These CSIs represent unique, synapomorphic characteristics that suggest common ancestry within Verrucomicrobiota and an independent lineage amidst other bacteria. CSIs have also been found that are shared by Verrucomicrobiota and Chlamydiota exclusively of all other bacteria. These CSIs provide evidence that Chlamydiota is the closest relative to Verrucomicrobiota, and that they are more closely related to one another than to the Planctomycetales. Verrucomicrobiota might belong in the clade Planctobacteria in the larger clade Gracilicutes. In 2008, the whole genome of Methylacidiphilum infernorum (2.3 Mbp) was published. On the single circular chromosome, 2473 predicted proteins were found, 731 of which had no detectable homologs. These analyses also revealed many possible homologies with Pseudomonadota.
Phylogeny
Taxonomy The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI).
Genus ?"Ca. Epixenosoma" Bauer et al. 2005 Genus ?"Ca. Nucleicoccus" corrig. Sato et al. 2014 Genus ?"Ca. Organicella" Williams et al. 2021 Genus ?"Ca. Rhizospheria" Nunes da Rocha 2010 Class Opitutia corrig. Choo et al. 2007 Order Opitutales Choo et al. 2007 Family Alterococcaceae Min et al. 2023 Family Cerasicoccaceae Min et al. 2023 Family Coraliomargaritaceae Min et al. 20232 Family Intestinicryptomonadaceae corrig. Hitch et al. 2025 ["Merdousiaceae" Pallen, Rodriguez-R & Alikhan 2022] Family "Moanibacteraceae" Pallen, Rodriguez-R & Alikhan 2022 [UBA2987] Family Oceanipulchritudinaceae Min et al. 2023 Family Opitutaceae Choo et al. 2007 Family Pelagicoccaceae Min et al. 2023 Family Puniceicoccaceae Choo et al. 2007 Family "Seribacteraceae" Wilkie & Olrellana 2024 ["Fogupanaceae" Pallen, Rodriguez-R & Alikhan 2022] Family "Spyradosomataceae" Pallen, Rodriguez-R & Alikhan 2022 [UBA953] Class Verrucomicrobiia corrig. Hedlund, Gosink & Staley 1998 ["Methylacidiphilae"; "Pedosphaerae" Brewer et al. 2016; Terrimicrobiia corrig. García-López et al. 2020] Order Limisphaerales Podosokorskaya et al. 2023 ["Pedosphaerales"] Family Fontisphaeraceae Podosokorskaya et al. 2023 Family Limisphaeraceae Podosokorskaya et al. 2023 Family "Pedosphaeraceae" ?Tsitko et al. 2014 Order Methylacidiphilales Awala et al. 2023 Family Methylacidiphilaceae Awala et al. 2023 Order Terrimicrobiales García-López et al. 2020 ["Chthoniobacterales" Sangwan et al. 2004] Family "Chthoniobacteraceae" Sangwan et al. 2004 Family Terrimicrobiaceae García-López et al. 2020 Family "Udaeobacteraceae" Pallen, Rodriguez-R & Alikhan 2022 [UBA10450] Family "Xiphinematobacteraceae" Order Verrucomicrobiales Ward-Rainey et al. 1996 Family Akkermansiaceae Hedlund & Derrien 2012 [Rubritaleaceae Hedlund 2012] Family "Sulfuriroseicoccus" Feng et al. 2022 {SLCJ01} Family Verrucomicrobiaceae Ward-Rainey et al. 1996
See also List of bacterial orders List of bacteria genera
References


