A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane. As a result, vesicular transporters govern the concentration of molecules within a vesicle.
Types Examples include:
Archain ARFs Clathrin Caveolin Dynamin and related proteins, such as the EHD protein family Rab proteins SNAREs Vesicular transport adaptor proteins e.g. Sorting nexins Synaptotagmin TRAPP complex Synaptophysin Auxilin
Pathways There are multiple pathways, each using its own coat and GTPase.
COP 1 (Cytosolic coat protein complex ) : retrograde transport; Golgi → Endoplasmic reticulum COP 2 (Cytosolic coat protein complex ) : anterograde transport; RER →cis-Golgi Clathrin : trans-Golgi → Lysosomes, Plasma membrane → Endosomes (receptor-mediated endocytosis)
See also Membrane transport protein Wikipedia:MeSH D12.776#MeSH D12.776.543.990 --- vesicular transport proteins
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