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chemistry

WAY-214156

WAY-214156 is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand WAY-214156 rather than just read about it. In short: WAY-214156 is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It is 100-fold selective for the ERβ over the ERα with an IC50 of 4.2 nM (compare to estradiol with IC50 values of ~3–4 nM for both the ERα and ERβ).

WAY-214156 — main illustration
WAY-214156 — illustration

Key takeaways

  • WAY-214156 belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect WAY-214156 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of WAY-214156 from memory before moving on to harder problems.

Reference excerpt

WAY-214156 is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It is 100-fold selective for the ERβ over the ERα with an IC50 of 4.2 nM (compare to estradiol with IC50 values of ~3–4 nM for both the ERα and ERβ). The drug is less selective for the ERβ than is prinaberel (ERB-041, WAY-202041), another selective ERβ agonist, but is more potent in comparison. WAY-214156 may produce anti-inflammatory effects via the ERβ and has been proposed as a potential treatment for inflammatory conditions such as rheumatoid arthritis.

See also 8β-VE2 Diarylpropionitrile ERB-196 FERb 033 WAY-166818 WAY-200070

References

Illustrations

WAY-214156 illustration

Worked examples

Example 1 — a first encounter with WAY-214156

Start with the simplest possible case. Write down what WAY-214156 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to WAY-214156 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about WAY-214156 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of WAY-214156

In research
WAY-214156 appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses WAY-214156 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
WAY-214156 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genito-urinary system drug stubs, Heterocyclic compounds with 4 rings, Hydroxyarenes, so understanding it makes those chapters shorter.
In everyday life
Look for WAY-214156 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study WAY-214156 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what WAY-214156 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain WAY-214156 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is WAY-214156 in simple terms?

WAY-214156 is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It is 100-fold selective for the ERβ over the ERα with an IC50 of 4.2 nM (compare to estradiol with IC50 values of ~3–4 nM for both the ERα and ERβ).

Why does WAY-214156 matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study WAY-214156?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on WAY-214156.

Tags

  • Genito-urinary system drug stubs
  • Heterocyclic compounds with 4 rings
  • Hydroxyarenes
  • Nitriles
  • Oxygen heterocycles
  • Selective ERβ agonists
  • Synthetic estrogens

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