biology

WD repeat-containing protein 11

WD repeat-containing protein 11 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand WD repeat-containing protein 11 rather than just read about it. In short: WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by the WDR11 gene. Function This gene encodes a member of the WD repeat protein family.

Key takeaways

WD repeat-containing protein 11 belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect WD repeat-containing protein 11 to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of WD repeat-containing protein 11 from memory before moving on to harder problems.

Reference excerpt

WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by the WDR11 gene.

Function This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. WDR11 has been shown to be part of a trimer with FAM91A1 (Family With Sequence Similarity 91 Member A1) and C17orf75, as elicited through immunoprecipitation, fractionation, and mass spectrometry. This trimer has been proposed to promote the Golgi’s capture of vesicles. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Clinical significance This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

References

Illustrations

Worked examples

Example 1 — a first encounter with WD repeat-containing protein 11

Start with the simplest possible case. Write down what WD repeat-containing protein 11 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to WD repeat-containing protein 11 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about WD repeat-containing protein 11 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of WD repeat-containing protein 11

In research: WD repeat-containing protein 11 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses WD repeat-containing protein 11 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: WD repeat-containing protein 11 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 10, Human chromosome 10 gene stubs, so understanding it makes those chapters shorter.
In everyday life: Look for WD repeat-containing protein 11 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study WD repeat-containing protein 11 in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what WD repeat-containing protein 11 means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain WD repeat-containing protein 11 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is WD repeat-containing protein 11 in simple terms?

WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by the WDR11 gene. Function This gene encodes a member of the WD repeat protein family.

Why does WD repeat-containing protein 11 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study WD repeat-containing protein 11?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on WD repeat-containing protein 11.