science

Wogonin

Wogonin is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Wogonin rather than just read about it. In short: Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis. The glycosides of wogonin are known as wogonosides.

Key takeaways

Wogonin belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Wogonin to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Wogonin from memory before moving on to harder problems.

Reference excerpt

Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis. The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from Oroxylum indicum. It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement.

Pharmacology Wogonin has been found in one study to have anxiolytic properties in mice at doses of 7.5 to 30 mg/kg, without exhibiting the sedative and muscle-relaxing properties of benzodiazepines. Preliminary in vitro studies have shown pharmacological effects that indicate wogonin may have anti-tumor properties. Wogonin has also been found to possess anticonvulsant effects. It acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with a binding affinity of Ki 0.92 μM and an IC50 value of 1.26 μM which is about 100 times less potent than diazepam (IC50 value of 0.012 μM). The LD50 of pure Wogonin in mice is 3.9 g/kg of body weight suggesting low toxicity. CNS review:

Illustrations

Worked examples

Example 1 — a first encounter with Wogonin

Start with the simplest possible case. Write down what Wogonin claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Wogonin before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Wogonin ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Wogonin

In research: Wogonin appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Wogonin in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Wogonin is common in secondary-school and first-year university syllabi. It links to neighbouring topics Anticonvulsants, Anxiolytics, GABAA receptor positive allosteric modulators, so understanding it makes those chapters shorter.
In everyday life: Look for Wogonin outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Wogonin in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Wogonin means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Wogonin out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Wogonin in simple terms?

Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis. The glycosides of wogonin are known as wogonosides.

Why does Wogonin matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Wogonin?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Wogonin.