astronomy

Wolfgang Löscher

Wolfgang Löscher is a astronomy topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Wolfgang Löscher rather than just read about it. In short: Wolfgang Löscher (born 3 October 1949, Berlin, Germany) is a veterinary medicine researcher. He is currently a Guest Scientist at the Hannover Medical School and Head of the Translational Neuropharmacology Lab of the Department of Experimental Otology of the ENT Clinics.

Key takeaways

Wolfgang Löscher belongs to astronomy; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Wolfgang Löscher to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Wolfgang Löscher from memory before moving on to harder problems.

Reference excerpt

Wolfgang Löscher (born 3 October 1949, Berlin, Germany) is a veterinary medicine researcher. He is currently a Guest Scientist at the Hannover Medical School and Head of the Translational Neuropharmacology Lab of the Department of Experimental Otology of the ENT Clinics. He is also Professor and former Chair at the Department of Pharmacology, Toxicology, and Pharmacy at the University of Veterinary Medicine Hannover, Germany and also a member of the National Academy of Sciences Leopoldina.

Education Löscher graduated from the Free University of Berlin in 1974 with a degree in veterinary medicine, and later obtained his doctoral degree (Dr.med.vet.) from the same university.

Research and career Löscher did postdoctoral research work for five years particularly in neuropharmacology and toxicology in Germany, Denmark, and the US. His research interests include pharmacology of antiepileptic (antiseizure) drugs, the mechanisms of antiseizure drugs, and the pathophysiology of temporal lobe epilepsy with the aim to find new targets for treatment and also evaluated antiepileptic drugs for dogs. While at FU Berlin, Löscher worked alongside Hans-Hasso Frey to pioneer neurochemical studies of antiepileptic drugs such as valproate on the synthesis and metabolism of the inhibitory neurotransmitter GABA. After his move to Hannover in 1987, models and mechanisms of resistance to antiepileptic drugs developed into one of the major research areas of Löscher group. During the first years of his career, he worked as a visiting scientist at the National Institute of Health in Bethesda, Maryland, USA. During his tenure at the University of Veterinary Medicine Hannover (from 1987-2019), he was full Professor and Director of the Department of Pharmacology, Toxicology, and Pharmacy. In 2019, he retired from the chair position to become a research professor and head of an epilepsy research group at the University of Veterinary Medicine, Hannover. In 2023, he moved to the Hannover Medical School as a Guest Scientist and became Head of the Translational Neuropharmacology Lab of the Department of Experimental Otology of the ENT Clinics at the NIFE. Since 2002, Löscher has been Head of the Center of Systems Neuroscience (ZSN) in Hannover.

Awards and honors In 1980, Löscher received the Alfred Hauptmann Award by the Epilepsy Board of Trustees. Additional awards include the Magyar-Kossa Memorial Medal and the Ambassador for Epilepsy research Award of the International League against epilepsy. He won a Walter Frei prize from the University of Zurich and European Epileptology Award from ILAE (International League Against Epilepsy) in the year 2014.

Publications Löscher, Wolfgang; Schmidt, Dieter (1988-05-01). "Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations". Epilepsy Research. 2 (3): 145–181. doi:10.1016/0920-1211(88)90054-X. ISSN 0920-1211. PMID 3058469. S2CID 12643651. Löscher, Wolfgang; Potschka, Heidrun (2005-08-01). "Drug resistance in brain diseases and the role of drug efflux transporters". Nature Reviews Neuroscience. 6 (8): 591–602. doi:10.1038/nrn1728. ISSN 1471-0048. PMID 16025095. S2CID 20356482. Löscher, Wolfgang; Potschka, Heidrun (2005-01-01). "Blood-brain barrier active efflux transporters: ATP-binding cassette gene family". NeuroRx. 2 (1): 86–98. doi:10.1602/neurorx.2.1.86. ISSN 1545-5343. PMC 539326. PMID 15717060. Löscher, Wolfgang (2011-06-01). "Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs". Seizure: European Journal of Epilepsy. 20 (5): 359–368. doi:10.1016/j.seizure.2011.01.003. ISSN 1059-1311. PMID 21292505. Löscher, Wolfgang; Potschka, Heidrun (2005-05-01). "Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases". Progress in Neurobiology. 76 (1): 22–76. doi:10.1016/j.pneurobio.2005.04.006. ISSN 0301-0082. PMID 16011870. S2CID 38977116.

References

Illustrations

Worked examples

Example 1 — a first encounter with Wolfgang Löscher

Start with the simplest possible case. Write down what Wolfgang Löscher claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In astronomy, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Wolfgang Löscher before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Wolfgang Löscher ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Wolfgang Löscher

In research: Wolfgang Löscher appears in astronomy research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Wolfgang Löscher in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Wolfgang Löscher is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1949 births, Epileptologists, Free University of Berlin alumni, so understanding it makes those chapters shorter.
In everyday life: Look for Wolfgang Löscher outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Wolfgang Löscher in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Wolfgang Löscher means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Wolfgang Löscher out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Wolfgang Löscher in simple terms?

Why does Wolfgang Löscher matter?

Because it connects several astronomy ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Wolfgang Löscher?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Wolfgang Löscher.